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Dosing Science

Onset & Duration Timeline

How different consumption methods affect onset, peak intensity, and total duration — based on published clinical data.

Dosing Reference

Level Inhaled Edibles Concentrates
Microdose 1 small puff 2.5 mg THC Not recommended
Beginner 1–2 puffs 5 mg THC Not recommended
Standard 3–5 puffs 10–15 mg THC Rice-grain size dab
Experienced Full joint / bowl 20–50 mg THC Standard dab

Sources

  • National Institute on Drug Abuse (NIDA) — Cannabis DrugFacts: Onset and duration by method
  • Huestis, M.A. (2007). Human Cannabinoid Pharmacokinetics. Chemistry & Biodiversity, 4(8), 1770–1804
  • Wall, M.E. et al. (1983). Metabolism, disposition, and kinetics of delta-9-THC in men and women. Clinical Pharmacology & Therapeutics, 34(3), 352–363
  • Vandrey, R. et al. (2017). Pharmacokinetic Profile of Oral Cannabis. Drug and Alcohol Dependence, 180, 367–370
  • Colorado Department of Public Health & Environment — Recommended dosing guidelines
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